THE ROLE OF THE REDOX SIGNALING MOLECULES
We have been considering the healing process in a series of articles, reviewing atomic physicist Dr. Gary Samuelson’s booklet The Science of Healing Revealed. This final installation in the series will rap up our summary of the series and review the role of the Redox Signaling Molecules in the healing process. Enjoy!
Cleaning Up the Mess
Let us take a look once more at the cell’s clean-up crew and how important they are to the healing process. These special enzymes (proteases and antioxidants) are made to rip apart the molecules that make up the micro machinery, messengers and reactive molecules of the cell and recycle their pieces. Without them, garbage would build up everywhere inside and outside of the cells and the cells would soon die. Besides, the homeostatic balancing act in the cell absolutely depends on them. The cell is constantly manufacturing new molecules and requires a crew to take the old ones apart in order to maintain this balance.
The clean-up crew also has the job of cleaning up all of the “toxins” (left-over proteins) after the immune system or programmed suicide has kilted invaders or dysfunctional cells. In this sense, they form an essential part of the immune system also.
Regeneration of Lost Tissues
After the damage has been cleaned up and the oxidative stress condition has been corrected by eliminating the excess oxidants, there is still the job of replacing the cells that have been lost. You get the mental picture of many rows of ordered cells with holes and large gaps in them where cells have died and been cleaned up. The reconstruction is done by the cells that are surrounding the holes and gaps. Since cells are constantly sending messages back and forth between neighbors, they notice when one of their neighbors is missing. After the emergency distress condition is over in the neighborhood, the intercellular communication channels are reinforced and the holes become obvious to the neighboring cells. The cells are also free to divide and reproduce again.
At that point, the healthy neighboring cells start to divide in order to fill in the gaps, reconstructing new tissues as they go. If ample blood supply is not available for the new cells, they send out distress messengers that will cause new blood vessels to grow to supply them. The job is done when each of the cells is surrounded by their regular group of neighbors. This same simple reconstruction condition also applies to growing tubular blood vessels that supply the cells, the ring of leading cells will continue to divide and build the vessel until it encounters another blood vessel to link into.
Oxidants Play Central Roles as Messengers
How interesting it is when we can trace all of the complex mysteries of the healing process back to a simple set of rules that each of the cells follow. How interesting it is to discover the huge and important role that oxidants and antioxidants have in this healing process. When damage occurs, the oxidants become the red flags that mark out where and how much damage has been done. What would happen if the oxidants were not there to flag the damage?
Toxins, radiation, infections, cuts, scrapes, bruises, oxygen starvation and any other form of damage would go undetected and neglected without oxidants. Healing would be Impossible. It is this continual balance between the production of oxidants and reductants and their eventual elimination by the antioxidants that allows the cells to react to the damage. It is the response to the resulting imbalance of oxidants (or oxidative stress) that allows the cells and tissues to respond and heal themselves.This is the new picture emerging from the biosciences on healing.”
This completes our series on the Healing Process. I trust you have a better understanding of and a deeper appreciating for the healing process and the essential role the Redox Signaling Molecules play in it. Enough, anyway, to motivate you toward ordering a couple of bottles of ASEA and keep a supply on hand throughout the year. Just 2 oz a day, served up in a glass container (not metal or plastic) and taken on an empty stomach, will supply your body-cells with ample signaling molecules throughout the day. Click HERE to place your order.
I want to thank you for your business and for following my blog. We’re off to Colorado for three weeks vacation. This will give you a chance to catch up with articles you haven’t had time to read or finish yet. I apologize for their length, but I wanted to be as thorough and comprehensive as possible. I’ll be back with a new post shortly. Until then,
My best to you, your health and your healing,
Dr. Tony Palombo
Visit my second web blog for a meditation on Your Sacred Heart and Attunement with Sacred Sound
These next final posts will conclude my review of Dr. Gary L. Samuelson’s booklet The Science of Healing Revealed. I hope you are finding this series as fascinating as I am. Just to behold the intricacies of cellular life and understand what all goes into the healing process is awe inspiring. So, let’s begin our summary. But first a video clip of ABC’s report on the inner life of the cell. (Enjoy the full Inner Life of the Cell with wonderful music.)
NEW INSIGHTS-THE FRAMEWORK OF THE BODY’S NATURAL HEALING PROCESS
It is now time to take a step back, and look at the whole developing picture. We have already assembled many of the edge pieces in the puzzle and put together some of the more obvious patterns. We have also placed some more pieces in this framework and examined where they might go. What do we see when we step back and stare at everything we have assembled so far? Let us look at this picture in the light that the revealed mysteries of how the body naturally heals itself will unlock the secrets of sustained health for us and the following generations.
Much of the material in this chapter should sound familiar. It is just a capitulation of the major points in this booklet all written in a few pages so that the overall picture becomes clearer.
Detecting and Locating the Damage Zone — Redox Signaling
We see a pattern: in order for the body to heal itself it must be able to detect and locate the damaged cells. This task goes to the cellular-distress messengers. These messengers are sent out in response to a distress condition inside the cell. This distress condition occurs in the cell when something interferes with the normal cellular processes and disturbs the normal homeostatic chemical balance. This homeostatic chemical balance depends on the cell being able to constantly produce the thousands of critical molecules it needs and then being able to break them down at the same rate that they are being produced. When this balance is disturbed, certain molecules are either building up in the cell or becoming depleted. These excesses or deficiencies cause transcription-factor messengers to be sent into the DNA that change certain production rates that hopefully will ultimately compensate for the imbalance. Sometimes the response includes an increase in the amount of messengers sent out to signal this condition to other cells.
We start to see that wherever we look, the most reliable indicator of cellular distress is the build-up of oxidants in the cell, a condition called “oxidative stress” that occurs universally, even in different species and plants. The simple reactive oxidants and reductants produced in the cell are formed from the sea-water molecules that fill our cells. These small reactive molecules have the capacity of strongly affecting the redox potential of the sea-water environment where all of the complex processes of life take place. They are the redox messengers that send the redox signals governing much of the healing process. These reactive molecules are mainly produced in the mitochondria during the metabolism of sugars in the same process that produces the ATP that fuels the cell.
The antioxidants that the cell manufactures in order to break down these reactive molecules are very plentiful, ubiquitous all throughout the cell. The primary function of the antioxidants is to combine and neutralize equal quantities of reductants and oxidants and keep them from damaging the sensitive areas of the cell. It soon becomes clear that these small reactive molecules, a balanced mixture of oxidants and reductants, are critical to the proper function of the cell and even more essential to the damage control mechanisms that exist inside and outside the cell.
The Cell’s Response to Damage
Careful research has been done on the effects of oxidative stress resulting from cellular damage. The overabundance of oxidants (ROS) in the cellular environment has been shown to activate several genetic buttons on the cell’s master control panel. Some of the buttons pressed are shown below (in approximate order of activation):
- DNA Repair Button – Sends out the DNA damage detection
and repair crew
- Antioxidant Boost Button -Increases production of
- Stronger Intercellular Communication Button – Puts up
stronger communication lines.
- Increase Blood Supply Button – Opens local blood vessels wider
- Stronger Cell Adhesion Button – Sticks the cells together stronger
- Inflame Tissues Button – Stops the spread of damage to other cells
- Secrete Antibiotics Button – Antibacterial countermeasures deployed
- Stop Cell Division Button – Shuts down the cell’s ability to replicate itself
- Send Distress Call button – Sends a distress signal to the immune system
- More Energy to Repair Crew Button – Diverts more energy to repair processes
- Prepare Cell for Shutdown Signal Button – Polls neighbors for final decision
- Master Shutdown Button – Kill and dismantle the cell
If the oxidative stress condition is fixed by the repairs, then the DNA does not continue pressing more buttons; in fact it starts deactivating the buttons already pushed and returns to normal operation. It would be nice if we could press a few of these genetic buttons even if there is no oxidative stress; the “Repair DNA” and “Antioxidant Boost” button, for example, look pretty good. Perhaps we could take an “Antioxidant boost” pill that would do the job. We will discuss some of the possibilities later on.
In my next post we will review how the cell’s clean-up crew clear the way for the regeneration of new tissue and how oxidants (free radicals) play a central role as messengers.
But before you leave my blog, enjoy Dr. Bolinski’s video clip on the fascinating life of the cell and be awed by life’s intricate design and inspired to take better care of your body. I’ve added three more clips, two that summarize what Redox Signaling is and the third one to tell you about ASEA, a revolutionary product that I am getting behind because of its promising health and longevity benefits to my patients and clients. I’m taking it daily and it has made a huge difference in my energy level and the quality of my sleep. Just knowing that my cells are able to communicate with one another gives my mind rest from anxiety over ageing. There’s nothing like it on the market. Enjoy!
Until next we meet,
Here’s to your health and healing!
Dr. Tony Palombo
Wholeness Is – All Things are Connected
The Healing Process is as much an unfolding and revelation of what is already whole and holy, namely Life, as it is a mending to make whole what has become partial, fragmented and isolated from the whole, if only in consciousness and in perception. The reality is oneness. All things are connected and cannot be otherwise disconnected, anymore than ripples on the surface of a pond created by two or more pebbles thrown in separate places into the pond can be separated. The ripples can be seen as vibrational waves connecting all forms of life afloat in cosmic space. “Pluck a flower and disturb a star.”
Life is Spirit and Spirit is present everywhere as the Presence of Love. Love is all and all is love, and the essence of Love is Oneness. Therefore, as we give consideration to the human immune system, I would invite you to begin by seeing all of Life as ONE and as the manifestation and action of Love . . . and Love does not attack Love.
In the medical model of the immune system, as you are about to see in these next video clips, as well as in the passage from Dr. Gary Samuelson’s booklet The Science of Healing Revealed – New Insights into Redox Signaling, Life’s intricate parts are pitted against one another in a battle over the flesh-and-blood terrain of the whole organism of our physical bodies. Pathogens are characterized as “invaders” while anti-bodies as “killer cells” bent on destroying the invaders as “enemies” to the self whom they serve at all costs. This is all part of the drama Louis Pasteur’s germ theory has given rise to in the paranoid and morbid imagination of human hearts and minds. This mind-set has only weakened our natural immunity by instilling fear in our hearts. Fear shuts down our immune system.
In reality, there is nothing to fear, as nothing is “wrong.” Everything matters. Pathogens have as much right to existence as human beings. They are part of the Creative Process in which they play an essential role. What, for instance, would happen to cadavers if pathogens didn’t break them down and return them to the dust from which they were formed? That’s their job, and if they find sick and dying cells while passing through our bodies, it is their job to take them out and scavenge the debris. They would not do so if they found no sick and dying cells, an unlikely occasion considering the oxidative stress under which our body-cells exist and operate on a daily basis. It’s the law of the survival of the fittest at work that is operative throughout the natural world.
So, keep this in mind as we take a look at how the immune system deals with non-self visitors through the eyes of traditional medicine with its “germ-theory” mind-set that has dominated our consciousness during the last century, a mind-set that forms the basis of our so-called “healthcare system” today, which would be more accurately called a “disease management” system. Enjoy and be enlightened by what follows, remembering to see it all from a larger perspective of the Whole.
Comment on the video clips: Medical overlay aside, it is fascinating to see the infinite microcosm at work in such detail within our bodies, and it is all governed and directed by the law of resonance and attraction. I see “T” cells and white blood cells, for instance, absorbing pathogens as “grist for the mill,” thereby reclaiming and incorporating their substance and energy back into the functional whole, transforming and transmuting them in the process. Perhaps “T” cells would more accurately be called “Transmuting cells” rather then “killer cells.” Keeping this perspective in mind, let’s see what Dr. Samuelson has to say about the immune system and the Redox Signaling Molecule.
Immune System’s Response to a Threat
The immune system in higher vertebrates is complex and highlydeveloped and yet it is built around principles that exist in even the most primitive species and plants (plants really do have an immune system). The innate immune response in plants and in lower and higher animals depends on a redox signaling process (messengers of distress) to help the organism identify and destroy its enemies. The principle is simple: if anything foreign causes enough damage to result in acute oxidative stress, as explained, then it is an enemy.
It is convenient that the redox messengers (the oxidants that signal that damage has occurred) are also the most potent oxidative ammunition available with which to load the cannons and kill the enemy. The presence of all these harmful oxidants, though, requires that these forms of life produce a complement of antioxidants with the ability to neutralize any stray oxidants before they can cause damage to the organism itself. The antioxidants found in plants, by the way, are not necessarily the same as those used in higher life forms. Eating a berry that has plant antioxidants will not generally supplement the native antioxidants utilized inside your cells. Plant antioxidants, however, can be helpful as they can make it into your blood and help reduce the stray oxidants there. Note that some antioxidants, such as vitamin-C, are indeed able to be absorbed by tissues.
In humans and higher vertebrates, there are a variety of antioxidants and “clean-up-crew” enzymes that clean up the toxic mess once the battle is over. In these higher animals, there also exists an intricate adaptive immune system that can use the remaining scraps from the battle to identify, tag, and keep a list of harmful foreign invaders. This allows a quicker and more specific immune response, overall, and thus a higher survival rate. One drawback of this improved immune system, none-the-less, is that friendly and inert objects can mistakenly be identified as enemies.
One powerful advantage that the redox signaling system offers is aclear identification that the battle has been won. When the oxidative stress condition subsides, it is a sign that the battle is over and is a signal to start rebuilding. In the process of regenerating the lost tissues, these redox-induced messengers are used again to help the newly forming tissues signal that they need oxygen and nutrients. These messengers then spur on the vascular growth needed to feed these new tissues. The healing process is beautifully simple in principle and amazingly complex in its application. Cells must be able to identify when they are in distress and then call up the appropriate action to correct the situation. Stress leads to imbalance which in turn leads to the action needed to reestablish balance. The ability to maintain balance is an essential ingredient of life.
Raspberries – Life’s perfection in an imperfect world
Of course, we do not live in a perfect world and our bodies are sometimes less than capable of handling the insults constantly being slung at them by our toxic mind-made world of chemicals, estrogenic plastics, and insecticides in our foods. Knowing this perhaps, Mother Nature has provided us with perfect foods that have built-in immune-system support nutrients. The humble red raspberry contains “ellagic acid” which is anti-viral, anti-bacterial, anti-fungal, anti-cancer, making it a natural anti-biotic.
Another anti-pathogen can be found within the seed of the grapefruit, put there, no doubt, by Mother Nature to protect the germ in the seed from destruction by fungi and other pathogens. It’s a very bitter oil, as you know if you’ve ever bit into a grapefruit seed. The oil has been extracted and made available in various “citracidal” preparations, such as Triguard Plus ($15 plus postage). It is anti bacterial, anti-fungal, anti-yeast and effective against some 27 different pathogens. It is completely harmless to the body cells, just don’t get it in your eyes as it will burn.
Check out the links below for an enlightening presentation of the humble raspberry and of ellagic acid, also available in capsule form from the company who brings you these video clips. Enjoy, and I’ll see you next blog post! Until then,Here’s to your health, healing and vitality!
Dr. Anthony Palombo
Email me at firstname.lastname@example.org to order Triguard Plus.