Understanding Calcium Functionally

There is more calcium in the human body than all the other minerals combined.  More calcium supplements are sold than any other mineral, but most of them are not absorbed from the GI tract.  Once absorbed, calcium has to be ionized before it can be utilized.  Not all forms of calcium can be easily ionized by the body.  Let’s take a look at how this works from a functional standpoint. 

Calcium Functions

Calcium serves many functions.  It forms the foundation of bones. It provides fuel for muscle contraction. It is essential for blood coagulation and nerve impulse.  It is used by the immune system in “fighting” infections. In a deficiency of sodium, it is used to buffer acid and maintain normal pH in the body fluids and tissue.

Calcium does not stand alone, however, even in the formation of bone.  Calcium is balanced proportionately by magnesium (5/1) and by phosphorus (10/4).  Magnesium controls calcium absorption and provides lubrication for muscle contraction.  Phosphorus opposes calcium and holds it in solution where it is needed in liquid form.  It’s also a systemic acidifier, which is important to the absorption of calcium in the GI tract.

Bone Composition

Your body needs a lot more than calcium to manufacture bones.  Bones are made of protein, minerals and vitamins.  Minerals present in bone are: calcium, magnesium, phosphorus, potassium, manganese, silica, iron, zinc, selenium, baron, sulphur, chromium, and dozens of others.  In order for bones to absorb the minerals Vitamin D must be present.  Collagen is also part of the bone and provides a matrix for bone formation.  As you can see, if you’re concerned about your bone health, you’ll need to take a full spectrum organic mineral supplement and trace minerals.  I will cover this topic in my next blog post.

The Role of Phosphorus

Phosphorus holds calcium in solution.  If the ratio between calcium and phosphorus becomes imbalanced, problems will arise.  If there is not enough phosphorus to hold the calcium in solution, the extra calcium will start precipitating out of the body fluids.  If it precipitates into your kidneys, it forms kidney stones.  If onto your teeth, it is called tartar.  If it’s in your bones, it’s called arthritis.  If in your blood vascular system, it’s called arterial sclerosis or calcified arteries.  If in your eyes, it’s called cataracts. All of these conditions are symptoms of phosphorus deficiency.  We need to take a phosphorous supplement that does not contain calcium to raise the phosphorous level, such as Phosfood Liquid by Standard Process Labs ($17/2 fl.oz.).  If the calcium level is low, then we have conditions like dental caries, the erosion of the teeth.  Looking at it from the dentist’s standpoint, this is the systemic cause of dental caries: high phosphorous, low calcium.  This does not mean we have too much phosphorous. It just means we don’t have enough calcium to buckled the phosphorous.

Absorption

Calcium requires an acid environment in the GI tract for proper absorption.  People who have an alkaline GI tract just can’t absorb and assimilate calcium well.  Standard Process Labs makes a Calcium Lactate which is comprised of five grains of calcium and one grain of magnesium citrate.  This makes the pH of the total product 5.2, which is on the acid side. Seven is neutral, which straight calcium would be.

A word of caution about iron supplements:  Too much calcium in the GI tract prevents the absorption of iron.  Therefore iron and calcium supplements should not be taken together.

Ionization   

Calcium has to be ionized before it can be utilized in the body. To ionize is to give an electrical charge to a molecule being ionized. This is accomplished in the blood stream by our body’s enzyme system. The ionization of minerals makes them functional in our body tissues. If calcium is not ionized, for example, it stays in the fluid. The only kind of calcium you can ionize in your body is calcium bicarbonate.  Calcium lactate changes to calcium bicarbonate in just one step.  Whereas, limestone (calcium carbonate) goes through about a dozen changes to become calcium bicarbonate.  Don’t confuse calcium bicarbonate with calcium carbonate.

Calcium bicarbonate cannot be taken in a tablet form.  It is present in spring water, but if you put that same spring water in a tea kettle and boil it, the soft organic calcium bicarbonate changes to hard inorganic calcium carbonate, which is insoluble.  It precipitates to the bottom of the tea kettle in the form of limestone.

Calcium carbonate cannot be easily ionized in the blood stream and therefore is not readily available for use in the body.  It is circulated around and eventually deposited in muscles and on bones or turned into kidney stones for elimination.  Most commercial calcium products, including TUMS and ROLLAIDS, are calcium carbonate.  Some calcium products are formulated with calcium citrate which can be ionized, although not as easily as calcium lactate.

Chelated Organic Calcium 

Inorganic calcium becomes organic when chelated by the organic acids produced by plant roots, which absorb the calcium along with other minerals in a slightly acid soil. That’s why soil pH is very important in the vegetable garden.  Humus soil is very conducive to mineral chelation and absorption.  This is one of the benefits of organic gardening.

Getting back to calcium bicarbonate, you can’t make calcium bicarbonate tablets because as soon as you start drying the bicarbonate it changes to calcium carbonate.  So the closest that we can come to calcium bicarbonate is calcium lactate.

Calcium Lactate is one of Standard Process’ most popular products.  This is not a dairy product as it contains no whey or lactose and is safe for people allergic to milk products or lactose intolerant.  It’s also very affordable at $6 for 90 tablets ($20/330T, $42/800T).  For bone calcium, Standard Process mixes calcium lactate with a parathyroid base in a product called Cal-Ma Plus, which sells for $22/90T, $74/330T.  If you order through me by email add $13 for drop-shipping.

In my next blog post, I will explain bone resorption and remodeling and how drugs like Fosamax disable this process in a futile attempt to reverse osteopenia and osteoporosis.

Here’s wishing you a Healthy and Happy New Year!

Dr. Tony Palombo

References:  John Courtney, former head of Research & Development for Standard Process, Inc. for thirty years, now deceased.  His comments on products in the Clinical Reference Guide manual are adapted for use in this blog.

The Healing Process: Series Summary Finale

THE ROLE OF THE REDOX SIGNALING MOLECULES

We have been considering the healing process in a series of articles, reviewing atomic physicist Dr. Gary Samuelson’s booklet The Science of Healing Revealed. This final installation in the series will rap up our summary of the series and review the role of the Redox Signaling Molecules in the healing process.  Enjoy!

Cleaning Up the Mess

Let us take a look once more at the cell’s clean-up crew and how important they are to the healing process. These special enzymes (proteases and antioxidants) are made to rip apart the molecules that make up the micro machinery, messengers and reactive molecules of the cell and recycle their pieces. Without them, garbage would build up everywhere inside and outside of the cells and the cells would soon die. Besides, the homeostatic balancing act in the cell absolutely depends on them. The cell is constantly manufacturing new molecules and requires a crew to take the old ones apart in order to maintain this balance.

The clean-up crew also has the job of cleaning up all of the “toxins” (left-over proteins) after the immune system or programmed suicide has kilted invaders or dysfunctional cells. In this sense, they form an essential part of the immune system also.

Regeneration of Lost Tissues

After the damage has been cleaned up and the oxidative stress condition has been corrected by eliminating the excess oxidants, there is still the job of replacing the cells that have been lost. You get the mental picture of many rows of ordered cells with holes and large gaps in them where cells have died and been cleaned up. The reconstruction is done by the cells that are surrounding the holes and gaps. Since cells are constantly sending messages back and forth between neighbors, they notice when one of their neighbors is missing. After the emergency distress condition is over in the neighborhood, the intercellular communication channels are reinforced and the holes become obvious to the neighboring cells. The cells are also free to divide and reproduce again.

At that point, the healthy neighboring cells start to divide in order to fill in the gaps, reconstructing new tissues as they go. If ample blood supply is not available for the new cells, they send out distress messengers that will cause new blood vessels to grow to supply them. The job is done when each of the cells is surrounded by their regular group of neighbors. This same simple reconstruction condition also applies to growing tubular blood vessels that supply the cells, the ring of leading cells will continue to divide and build the vessel until it encounters another blood vessel to link into.

Oxidants Play Central Roles as Messengers

How interesting it is when we can trace all of the complex mysteries of the healing process back to a simple set of rules that each of the cells follow. How interesting it is to discover the huge and important role that oxidants and antioxidants have in this healing process. When damage occurs, the oxidants become the red flags that mark out where and how much damage has been done. What would happen if the oxidants were not there to flag the damage?

Toxins, radiation, infections, cuts, scrapes, bruises, oxygen starvation and any other form of damage would go undetected and neglected without oxidants. Healing would be Impossible. It is this continual balance between the production of oxidants and reductants and their eventual elimination by the antioxidants that allows the cells to react to the damage. It is the response to the resulting imbalance of oxidants (or oxidative stress) that allows the cells and tissues to respond and heal themselves.This is the new picture emerging from the biosciences on healing.”   

This completes our series on the Healing Process.  I trust you have a better understanding of and a deeper appreciating for the healing process and the essential role the Redox Signaling Molecules play in it.  Enough, anyway, to motivate you toward ordering a couple of bottles of ASEA and keep a supply on  hand throughout the year.  Just 2 oz a day,  served up in a glass container (not metal or plastic) and taken on an empty stomach, will supply your body-cells with ample signaling molecules throughout the day. Click HERE to place your order.  

I want to thank you for your business and for following my blog.  We’re off to Colorado for three weeks vacation.  This will give you a chance to catch up with articles you haven’t had time to read or finish yet. I apologize for their length, but I wanted to be as thorough and comprehensive as possible.  I’ll be back with a new post shortly.  Until then, 

My best to you, your health and your healing,

Dr. Tony Palombo

Visit my second web blog for a meditation on Your Sacred Heart and Attunement with Sacred Sound

The Healing Process: Role of the Redox Signaling Molecule

Redox Regulation of the Healing Process – New Science

We have come to the crux of our considerations around the Healing Process.  In this post we will see exactly how the healing process works and what players are involved.  Again, Dr. Gary Samuelson will tell the story in his own easy-to-read words.  We will start with two video clips: one of the process called “Covalent Bonding” and the other on how free radicals and antioxidants work in order to help us better understand how “free radicals” (oxidants) do their damage and how the antioxidants neutralize and disarm them by a simple exchange of electrons between “oxidants” (electron donors ) and “reductants” (electron acceptors).  At the end of the day, restoration of balance is the goal of the healing process, as we shall see, and the “villains” of the free radicals turn out to be essential players in the process of maintaining homeostasis.  This, I promise, will be a fascinating read.  Enjoy!  (Newcomers to my blog would enjoy reading the previous posts in this series on The Healing Process for background information.)

Video clips: Covalent Bonding (4:32), Free Radicals vs Antioxidants  (4:30)

Redox Regulation of the Healing Processes-New Science

Emerging science from the past five years has solidly established that the chemical balance of small reactive redox messengers is essential to the healing process and the regulation of the immune system. These small reactive “redox” molecules participate in the same homeostatic balancing act that is used to balance the proper amount of the various proteins inside the cell (as we already have discussed). These redoxmessengers are constantly being produced, mostly by the mitochondria in the cells, and then constantly being eliminated at the same rate by a variety of protective enzymes (generally called antioxidants“) that are strategically stationed inside and outside of the cells.

Let us more closely examine these reactive “redoxmessengers for a minute. They are made from simple rearrangements of the atoms in H20, NaGI and N2 and are put together by special molecular complexes in the cell. Some examples of redox signaling molecules are H202, H02, HOCI and NO. About half of the redox messengers can be categorized as oxidantsand the other half, in fairness, can be categorized as “reductants.”  “Reductants” is a contrived nickname, the official name being energetic “electron acceptors.Oxidants, incidentally, can also be referred to as energetic “electron donors” in the same sense.

Not much is said about “Reductants” in the literature. In fact this nickname was just fashioned to be able to talk about this group of electron acceptors in this booklet. The basic concept, however, is very familiar to chemists and physicists. The laws of conservation of charge, mass and energy dictate that every time an oxidant is made from a neutral solution, a reductant or combination of reductants must concurrently be made to counterbalance it. The electron acceptors must balance out the electron donors. The ability of the resulting molecules to oxidize or reduce the molecules in their environment is referred to as the “redox” potential, a key player and motivator for all of the chemical reactions that take place in nature.

The name “redoxitself comes from the ability of these messengers to “REDuceand/or “OXidizemolecules in their environment. Reduction and oxidation are chemical terms that relate to the potential that the molecules have to “give away(oxidize) or accept(reduce) electrons to and from other molecules in their environment. As mentioned, all chemical reactions taking place in the cell depend on this redox potential in order to happen. Redox messengers have the ability to change the redox potential of their environment, thereby altering the chemical reactions that take place. Strong reductants and oxidants can both be harmful and destructive to the cell if they are allowed to wander around at will.

The oxidants, in particular, have made a really bad name for themselves; several of them are free radicals that have high energy, unpaired electrons that will blow apart whatever they come into contact with (like tiny molecular cannons). Oxidants will damage DNA, blow holes in cellular membranes, destroy important proteins, etc. The reductants are also hazardous, they will grab electrons away from molecules (with the ferocity of small molecular sharks), thereby causing destruction. To be perfectly clear, reductants are not antioxidants. Reductants are simply the chemical counterparts of oxidants (much like acids and bases). Antioxidants, on the other hand, are a class of much larger organic molecules produced by genetic coding that act as catalysts capable of facilitating the reverse chemical processes needed to ultimately untie” and neutralize both the oxidants and the reductants. Antioxidant cycles require both oxidants and reductants in order to work correctly.

Let us focus on the antioxidants for a minute. The antioxidants were historically considered as the heroes of the cell because they broke down the harmful oxidants by pulling them in and neutralizing them together with reductants, leaving just common harmless sea-water molecules in their wake. Over an antioxidant cycle (some of which are complex multi-step processes) the oxidants and reductants are neutralized [view clip], however the antioxidant itself remains unchanged, ready to do it all over again to the next set of oxidants and reductants. The antioxidant in this sense is a catalyst that speeds up the neutralization of oxidants with reductants and yet of itself remains unchanged. You can think of an antioxidant as a black box: reactive and potentially dangerous oxidants and reductants go into the box and harmless neutral sea-water molecules come out.

Ironically, the oxidants (that historically have been thought to be the villains) are now seen as central players to the healthy function of the cells. We have recently learned that we would not be able to live without either the reactive oxidants or the reductants. The truth be told, these tiny reactive molecules play an absolutely essential messenger role in our cells and tissues [my underscore]. The most critical aspect of healthy redox-messenger balance is in that the oxidants and reductants must be produced and eliminated in perfectly-balanced and equal portions. As long as there are equal portions of oxidants and reductants in the interior or exterior of the cell, the antioxidants can readily neutralize them both as fast as they are created. As discussed, the antioxidants need equal portions of oxidants and reductants in order to function, in the case of Glutathione (an abundant antioxidant made in our cells). The large mouth of the relatively huge antioxidant molecule lures in a reductant (that is electron hungryand then lures in an oxidant (that has an energetic electron to donate) and then pulls them both together into the “active site” in the middle. At the active site, the reductant and oxidant are combined together, neutralizing them both. The resulting harmless molecules float away.  The antioxidant is then free to do it all again. If there is an ample supply of reductants and oxidants in the neighborhood, one antioxidant molecule can typically neutralize tens of millions of oxidant molecules every second, as measured in the lab.  [Emphasis and underscores mine]

This was a eye-opener for me when I first read it, and I believe it is crucial to a better understanding of homeostasis.  There are no “good” and “bad” players in this microcosm of the biological universe that comprises our bodies.  There’s only “appropriate” and “inappropriate” based on place and timing, balance and imbalance.  To quote a poet friend and colleague, “Nothing is wrong.  Everything matters.”  

The antioxidants are purposefully manufactured, sent to and positioned around the areas of the cell, such as the nucleus, that are vulnerable to oxidative damage. As equal portions of oxidants and reductants approach these protected areas, the antioxidants standing guard around these areas pull them in and neutralize them both. The antioxidants are thus able to keep these potentially harmful reactive molecules away from protected areas and corral and use them for their own best purposes. Consequently, the immune system uses large amounts of such oxidants, along with strong demolition enzymes, as its weapon of choice against harmful invading bacteria and viruses. The foreign invaders do not even stand a chance against these potent weapons. After the invaders have been torn apart and destroyed by the enzymes and oxidants, the surrounding antioxidants standing guard and other enzymes clean up the mess, toxins and hazards.

THE HEALING PROCESS DESCRIBED

The key to understanding how this redox balancing process helps the body heal itself comes when considering what happens when the cells become damaged or defective for some reason or another. There are thousands of different processes with thousands of different proteins taking place everywhere inside the cell. When something is not working right, how does the cell detect the damage? The answer lies in the fact that as the normal homeostatic balance that exists in healthy cells is disturbed, somewhere in the cell there is either a build-up or deficiency of the normal quantity of proteins. There is a high probability that this
grow
ing imbalance will at some point make the metabolism of sugars less efficient. When this happens, the redox-messenger production in the mitochondria becomes unbalanced, producing many more oxidants than reductants or vice versa. In other words, the damage will ultimately manifest itself as a buildup of oxidants or reductants. This condition is called “oxidative stress” and is a real phenomenon seen (under the microscope) to occur in almost all defective or stressed cells (in both animals and plants).

An imbalance in the redox messengers, usually manifesting itself as oxidative stress, sends a clear signal that damage has occurred somewhere and that the cell is defective. The excess oxidants are not balanced by reductants and cannot be effectively neutralized by antioxidants. These oxidants end up causing even more damage to other parts of the cell. This clear signal for help causes the DNA to code for the “fixit crew” and cytokine messengers that are sent out to alert the immune system. If this imbalance (oxidative stress condition) is not corrected by the attempts of the fixit crew, the oxidants continue to build up. Then after about two hours, the fatally damaged cell starts a “programmed cell suicide” cascade (apoptosis) that will end up with the cell killing and dismantling itself. This is not a bad thing. Normal healthy neighboring cells will then be able to divide in order to fill in the vacancy. On the microscopic scale, this is essentially the healing process. [my underscore]

The oxidative stress condition in a stressed or damaged cell also causes the DNA to code for messengers to be sent to neighboring cells, advising them of its condition. Redox messengers can also be used as these intercellular messengers. If the damaged cell, such as those found in tumors, is not able to kill itself, then its neighboring healthy cells will send back “death domain” messengers as well as distress messengers to the immune system that will either cause the damaged cell to die or to be attacked by the immune system. This system is regularly used to detect and destroy practically all of the damaged and dysfunctional cells in the body. Remember, it only takes one undetected dysfunctional cell, out of the trillions that are successfully detected and killed, to start seeding an abnormal growth.”

This brings our series to a turning point.  The posts that will follow will look at the role of the immune system in healing and how this system is activated by the Redox Signaling Molecules.   View this video clip to prepare for the next consideration.

Clip:  The Healing Revolution – the Science Behind ASEA.

To your health and healing,

Dr. Tony Palombo

For information on ordering ASEA, click here.


The Healing Process: The Cell, Part 3 Communication

The Signaling Messengers

We’ve been entertained and edified by the inner life of the cell — how it’s “micro machinery” makes protein molecules from amino acids in the ribosomes and produces its own energy (ATP) in the mitochondria.  We will now move on to learn how these inner parts of the cells communicate with one another, as well as how the cells communicate among themselves and with the various systems of the body.  Again, I will call upon Dr. Gary Samuelson to help tell the story from his booklet The Science of Healing Revealed – New Insights into Redox Signaling.

Looking at the simple molecular keys that control the kinase fuel gates that energize the machinery in the living cell gives us a first glimpse at a very important class of molecules and proteins that act as messengers that are sent off to make sure specific things happen or do not happen. As can be imagined, these signaling messengers serve a very important role in the working of the cells. They send signals between the machinery in the cell that determines how the cell’s machinery operates and responds to the normal changes in its environment as well as drastic alarms like threats, damage, lack of oxygen, changes in temperature, the arrival of a nerve signal, etc. They can also be sent as long distance messengers to send signals between cells and tissues, as well as general messengers released into the blood and lymph that affect the working of whole systems throughout the entire body, like adrenaline for example. A few of these are listed below. The rest of this booklet, however, is focused on the emerging science that explains, in part, how signaling messengers do what they do and the processes that keeps them controlled and balanced when the body is healthy.

Redox messengers – Reactive Oxygen Species (ROS) and Reduced SpeCies (RS) — The smallest and most fundamental universal signaling molecules in the body are the simple but extremely important reactive molecules that are formed from combinations of the atoms (Na, CI, H, 0, N) readily found in the salt water bath that fills the inside of the cells (cytosol). All of life’s players mentioned so far float around in this bath and can be surrounded by a balanced mixture of these reactive molecules…. “

Dr. Samuelson lists a few of these reactive molecules, such as Superoxide,  Hydrogen Peroxide, Hypochiorous Acid, Nitric Oxide, only four of some 20 of them.  Then there are these players:

Charged metal ions Their movement alone makes the electric current that carries signals along our nerves and muscles. They also play signaling roles in hundreds of different life processes. Three examples or these are the Calcium ion (Ca2+), the Potassium ion (K+) and Sodium ion (Na+).

Cytokines  – The messengers that activate and regulate the immune system, controlling inflammation, white blood cell movement and natural cell death; Interleukins (regulate immune cells); Interferons (identify invaders,viruses).

Then there are the Endocrine messengers that control and regulate digestion, metabolism and organ function: Adrenaline, Insulin, Gastrin.  And the Hormone messengers that determine tissue growth and reproductive function: Testosterone, Estrogen and Progesterone.

Another group of fascinating players in the life of the cell are what are called the “Transcription Factors. These messengers cause the DNA inside the nucleus to call for increased production or reduction of certain specific proteins: NF-kappaB calls for inflammation; NRF2 calls for antioxidants; and TNF calls for tumor death.

Enzymes – the “break-it-down clean-it-up and recycle-it crew.”

There are enzymes in the cell that are assigned to the clean-up and recycling crew. They speed up the elimination of the cell’s “garbage,” breaking down the unneeded or excess molecules into smaller useful components.  Without these enzymes we would quickly die from the accumulation of excessive and possibly harmful unneeded molecules inside the cells.  They also protect the cells by breaking down toxins that come in from the outside environment.

In a very real sense, these enzymes are more than just the garbage disposal crew, they form an indispensable part of the system that maintains the chemical balance needed to sustain all of the life-critical processes that take place inside the cells. In the cell, molecules (large and small) are constantly in the process of being built up from smaller pieces and then torn back down into smaller pieces again.

Antioxiants – “The clean-up crew that is placed strategically in the cell, like guardians, to break down and eliminate the oxidants that would otherwise accumulate and cause damage.” They are: Glutathione Peroxldase (GPx) that breaks down various oxidants (free radicals), Superoxide Dismutase (SOD) that breaks down superoxides, and Catalase that breaks down hydrogen peroxide.

ProteasesThe large protein break-it-down crew, used as digestive enzymes to break down food and used by cells to break down unneeded or defective proteins.  They are Trypsin, Chyotrypsin and Pepsinogen.

Other “Staff Members” are: Collagen, Cholesterol, Glucose, Triglycerides, Prostaglandin, Quinine, Oleic Acid, Cocaine, Caffeine, Levidopa, and Histamine.

As we can see, there are many and varied types of “actors” playing various and sundry roles to make life possible in our bodies so that we can live and serve in this earthly plane of existence.  It’s helpful to have them placed in a context the way Dr. Samuelson does in his booklet.

In my next post we will learn how all these actors work together via the signaling messengers, whose crucial role it is to keep all the actors in touch with one another and all the systems of the body well-informed on what’s going on with each part and within the whole body. Then we will be prepared to study and learn the important role chemical balance plays in the healing process, and how the body keeps everything balanced.  Until then,  if you haven’t viewed it already, take the time now to enjoy David Bolinsky’s “Fantastic Voyage Inside the Cell” (10 min).

My best to your health and healing,

Dr. Tony Palombo











 

 

 

 

 

 

 

 









 





Not All “Free Radicals” Are Harmful

 

Tony Pics for SA BookSome free radicals are actually essential to life. Free radicals have acquired a rather notorious reputation.  Like with the news media and worldly events, we mostly hear about all the bad stuff they do to the body’s cells and their DNA. The good stuff often goes un-noticed and untold. One such essential “free radical” is the recently discovered and celebrated Redox Signaling Molecule. Before I tell you about it, however, let me create a little context that will help you understand its importance in your body.

Your cells are micro-models of your entire body. Your body has organs and its cells have organelles: they eat, they digest, they create energy, they excrete waste, they are regenerated, and they die.  Their health depends largely on the conditions of the terrain wherein they live and carry out their various roles in the body.  This post is about the health of this terrain of your physiology. Your body is only as healthy as its cells.  It lives and dies at the cellular level.

Cells are individuals complete unto themselves.  They are also gregarious.  They form communities of organs and systems and communicate with one another and with cells in other communities, such as the immune system – or what I prefer to call “immune alliance.”  (It’s an alliance by virtue of the involvement of and dependency on every cell, organ and system of the body.)  The immunity of the body is only as strong and balanced as the health and stability of the cell and its ability to communicate with and activate protective mechanisms such as antioxidants and “T” cells, or T lymphocytes.

T cells are the body’s exterminators. They destroy harmful bacteria, pathogens, toxins, viruses and even viral-infected cells.  They are made in the Thymus gland and bone marrow.  They often depend on the secondary lymphoid organs, such as the lymph nodes and spleen as sites where activation occurs, but they are also found in other tissues of the body, most conspicuously the liver, lungs, blood, reproductive tracts, and profusely throughout the intestinal tract.

Cells can be injured and damaged by “free radicals.”  When they are damaged they cannot function normally nor communicate with the rest of the cells in the body. But not all “free radicals” are equal, nor harmful.  So, let’s take a look at what they are.

Free radicals are oxygen-carrying atoms, molecules or ions with unpaired electrons looking for other molecules with unpaired electrons to bond with. They may have a positive, negative or zero charge.  The unpaired electrons cause radicals to be highly chemically reactive.  They pair up with other molecules, such as those of the cells, to which they bond and, in most cases, do damage through what is called “oxidative stress.”  Antioxidants, such as found in fresh fruits and vegetables, including Vitamins E and C, can protect the cell from free radical damage by a chemical reaction that simply neutralizes free radicals.  This is the purpose of antioxidants.

Hydrogen, for example, is an atom with a zero charge and an unpaired electron to which free radicals are easily attracted and bond.  Once they bond, they are no longer “free” and are thus rendered harmless.  This is why it is important to keep the pH (potential of Hydrogen) of the body’s fluid internal terrain balanced with plenty of raw fruits, vegetables and alkaline-ash foods (not to mention plenty of water, which is comprised of 2 Hydrogen and 1 Oxygen molecules). Too many acid-ash foods, such as meats and grains, deplete the alkaline reserve the body draws on throughout the day in order to keep the pH balanced.  Otherwise your body’s terrain becomes acidic making the cells very unhappy as the acidic fluids in which they live and function erodes their outer wall.

Free radicals also play an important role in combustion, plasma chemistry, biochemistry, and many other chemical processes, including human physiology.  For example, superoxide and nitric oxide regulate many biological processes, such as controlling vascular tone.  Such radicals can even be messengers in a phenomenon dubbed “redox signaling.”    [Chemial reactions in which one atom or compound is reduced (gains an electron and therefore energy) and another is oxidized (loses an electron and therefore energy) are called redox reactions.]

Redox signaling molecules are produced in the mitochondria of each cell, where your energy (ATP) comes from as well.  Two kinds are produced: antioxidant activators and immune system communicators.   Here’s a graphic:   [Also, this link will take you to a power-point presentation by Dr. Rob Ward of ASEA’s Scientific Advisory Council.  Dr. Ward focuses on the powerful holistic nature of redox signaling and how these amazing molecules empower our bodies! http://www.vimeo.com/17464658 ]

Redox signaling is the complex process within the cells wherein free radicals, reactive oxygen species (ROS) and other electronically activated radicals act as messengers in the biological system. It is basically the process that shows how cells in our body respond to oxidants and free radicals. Redox signaling is a continuous and crucial process, through which human cells communicate with each other and carry out vital body functions.    [Ref:  http://www.bewellbuzz.com/antiaging/redox-signaling/]

As demonstrated here, the immune system (T cells) is one such system activated by these redox signaling molecules.  These reactive molecules attach to receptor sites on the cells and convey signals and messages to them, thereby empowering them to perform specific functions.

Redox signaling molecules also activate antioxidants that protect the cells of the body from free-radical damage.  In fact, antioxidants are functional only when activated.  As you can see, these molecules are very important to life.

For a scientific explanation of ROS, click on this website: http://www.en.wikipedia.org/wiki/Reactive_oxygen_species#Oxidative_damage

If you haven’t heard of redox signaling molecules yet and the role they play in the body’s ability to maintain a high degree ofhealth and well-being, you are not alone. Despite the fact that these molecules are relatively unknown to the general public, researchinto the critical role they play in cellularhealthhas been going on for at least 30 years, if not longer.

For a layman-friendly explanation of the Redox Signaling Molecule, visit this website: http://www.hubpages.com/hub/Redox-Signaling-Molecules-The-Next-Health-and-Wellness-Breakthrough .  You will be thrilled and thank me for bringing this information to you at this time.

This complex process, which occurs naturally within the cells of the body, slows down as we age, contributing to the ageing process.  Damaged cells fail to produce sufficient quantities of these signaling molecules, and those that are produced are often unstable and ineffective.

This slowing down and consequent ageing can now be addressed through a recent scientific breakthrough which has found a way to stabilize the Redox Signaling Molecule and synthesize it for human consumption with significant results in health benefits.

For a visual demonstration of how these radical molecules work in the body, click on this link:  http://www.dranthonypalombo.teamasea.com/science.aspx.  Scroll down and click on “View the full video.”This is my website as an associate distributor for ASEA(TM) products. After viewing the video, you may contact me for further information about this innovative approach to health enhancement. I’m taking ASEA(TM) myself and have noted an increase in energy, stamina and mental acuity and clarity. That’s encouraging to a septuagenarian. Clients report that they are able to reduce the amount of supplements they are taking.   I feel good about this product and recommend it highly to my blog readers.

I wish you each one a very joyful Christmas and a New Year of abundant and healthy living.

Here’s to your good health,

Dr. Anthony Palombo

1722 Bilbo St., Lake Charles, LA 70601. Phone (337) 802-5510 – Email dranthonypalombo@live.com